Pediatric Pharmacology and Therapeutics

Hepatic disorders in children

The hepatic disorders in children are a persistent issue address over years. Some US based medical colleges and hospitals specialize in this area with active faculty strength of over 60 pediatric gastroenterologists. More than 35,000 patients are seen annually in ambulatory programs in each of thesis individual hospitals. Mostly cases of acute liver failure, Alagille syndrome, Alpha-1 antitrypsin deficiency (AATD), autoimmune hepatitis, Beckwith-Weidman syndrome, Bile acid synthesis defect, biliary atresia are received and treated. However, among the other hepatic disorders Budd-Chiari Syndrome, Caroni’s disease, Cirrhosis chronic liver failure, Crigler-Najjar syndrome, Cystic fibrosis liver disease, Glycogen storage disease (GSD), Hemochromatosis, Hepatoblastoma, Hypercholesterolemia, Metabolic diseases, Nonalcoholic fatty liver disease, Organic acidemias, Primary hyperoxaluria, Primary sclerosing cholangitis, Progressive familial intrahepatic cholestasis Tyrosinemia, Urea cycle defects, Viral Hepatitis, Wilson disease are also gaining importance over the past few years.